Registered Nurse Salary in St. Louis, MO
The average Registered Nurse in St. Louis, MO earns $87,210 per year, with most salaries falling between $70,965 and $99,180. That's 14% below the national average of $102,000 for this role.
Look up your exact salary — free →Registered Nurse pay by experience in St. Louis, MO
| Experience | Average | Typical range |
|---|---|---|
| Entry-level | $68,400 | $57,285 – $81,225 |
| Mid-level | $87,210 | $70,965 – $99,180 |
| Senior | $108,585 | $88,065 – $131,670 |
| Staff / Lead | $136,800 | $108,585 – $170,145 |
| Executive | $180,405 | $142,785 – $235,125 |
Salary percentiles (mid-level)
$79,515
$87,210
$93,195
Figures are modeled market estimates for St. Louis, MO based on Earnable's salary dataset, updated 2026. Your actual pay depends on company, skills, and negotiation — look up your exact number.
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